The Zika virus is likely to spread across nearly all of the Americas, the World Health Organization has warned.
The infection, which causes symptoms including mild fever, conjunctivitis and headache, has already been found in 21 countries in the Caribbean, North and South America.
It has been linked to thousands of babies being born with underdeveloped brains and some countries have advised women not to get pregnant.
No treatment or vaccine is available.
The virus is native to Africa and was first found to be spreading in the Americas in Brazil in May 2015.
The lack of any natural immunity in the Americas is thought to be helping the infection to spread rapidly.
Zika is transmitted by the bite of Aedes mosquitoes, which are found in all countries in the region except Canada and Chile.
In a statement, The Pan American Health Organization (PAHO), the regional office of the WHO, said: “PAHO anticipates that Zika virus will continue to spread and will likely reach all countries and territories of the region where Aedes mosquitoes are found.”
It also confirmed the virus had been detected in semen and there were was “one case of possible person-to-person sexual transmission” but further evidence was still needed.
Around 80% of infections do not result in symptoms.
But the biggest concern is the potential impact on babies developing in the womb. There have been around 4,000 cases of microcephaly – babies born with tiny brains – in Brazil alone since October.
PAHO warned pregnant women to be “especially careful” and to see their doctor before and after visiting areas affected by the virus.
Colombia, Ecuador, El Salvador and Jamaica last week recommended women delay pregnancies until more was known about the virus.
Although officially PAHO says “any decision to defer pregnancy is an individual one between a woman, her partner and her healthcare provider”.
It is advising people to protect themselves from the mosquitoes, which also spread dengue fever and chikungunya.
PAHO advice is to ensure all containers that can hold even small amounts of water should be emptied and cleaned to prevent mosquitoes breeding.
And that people should protect themselves by using insect repellent, covering up and keeping windows and doors closed.